The Mesopotamian League is a domestic competition for mythball clubs located in historical region situated within the Tigris–Euphrates river system (modern Iraq) and regions of Persian Gulf in Arabia.
>> Running Championship: Season 38
| # | Season | Team |
| 1 | 001 | Esagil Babylon |
| 2 | 002 | Esagil Babylon |
| 3 | 003 | Ishtar Assur |
| 4 | 004 | Esagil Babylon |
| 5 | 005 | Ziggurat Ur |
| 6 | 006 | Semiram Nineveh |
| 7 | 007 | Esagil Babylon |
| 8 | 008 | Uruk |
| 9 | 009 | Uruk |
| 10 | 010 | Esagil Babylon |
| 11 | 011 | Semiram Nineveh |
| 12 | 012 | Ziggurat Ur |
| 13 | 013 | Uruk |
| 14 | 014 | Esagil Babylon |
| 15 | 015 | Esagil Babylon |
| 16 | 016 | Ishtar Assur |
| 17 | 017 | Lagash |
| 18 | 018 | Semiram Nineveh |
| 19 | 019 | Ishtar Assur |
| 20 | 020 | Esagil Babylon |
| 21 | 021 | Ziggurat Ur |
| 22 | 022 | Ishtar Assur |
| 23 | 023 | Esagil Babylon |
| 24 | 024 | Esagil Babylon |
| 25 | 025 | Uruk |
| 26 | 026 | Ishtar Assur |
| 27 | 027 | Semiram Nineveh |
| 28 | 028 | Semiram Nineveh |
| 29 | 029 | Esagil Babylon |
| 30 | 030 | Tigrita Kalakh |
| 31 | 031 | Ishtar Assur |
| 32 | 032 | Esagil Babylon |
| 33 | 033 | Ishtar Assur |
| 34 | 034 | Tigrita Kalakh |
| 35 | 035 | Ishtar Assur |
| 36 | 036 | Semiram Nineveh |
| 37 | 037 | Tigrita Kalakh |
| # | Team | Titles |
| 1 | Esagil Babylon | 12 |
| 2 | Ishtar Assur | 8 |
| 3 | Semiram Nineveh | 6 |
| 4 | Uruk | 4 |
| 5 | Ziggurat Ur | 3 |
| 6 | Tigrita Kalakh | 3 |
| 7 | Lagash | 1 |
| 37 |